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Headache

This condition affects 80 – 90% of people per year

 Most headaches are not a serious risk to health

 A benign headache can be easily treated by taking an aspirin or other simple painkiller.

 Many types of headaches are the result of a stressful lifestyle

 However, headaches may be a warning sign of more serious disorders

 In diagnosing headaches, the patient’s history is all important

Description

Almost everyone suffers from a headache from time to time. Most headaches are transient annoyances that disappear with the help of an analgesic. But for one person in ten, a headache is an excruciating experience, and might herald some serious disorder.

About 15% of the population have headaches severe or frequent enough to consult a doctor. In fact, headache is the most common cause of pain which prompts patients to consult their GP.

Even children get headaches, some well before the age of ten. Before puberty, headaches are more common in boys.

In adults, headaches are four times more prevalent in women and often linked to menstrual fluctuations. In both sexes the frequency and severity of headaches decline with advancing years.

What are the causes?

  The most common cause of headache is scalp and neck "muscle contraction" or tension headache. This affects 20% of the population. Tension headaches are usually in relation to stress or anxiety.

  Vascular headaches, namely migraine and cluster headaches, make up the other large group of headaches – affecting 5 – 10% of the population.

Both tension and vascular headaches can occur in an individual at the same time. In practice, the distinction between these two entities is often less clear-cut, and there may be an element of both muscle tension and a vascular component at the same time.

 Headaches due to infection of surrounding structures: sinus infection, tonsillitis, toothache, meningitis.

  Headache due to inflammation of surrounding tissues: cervical spine arthritis, constant coughing, straining of the eyes, acute glaucoma, trigeminal neuralgia and temporal arteritis

  Certain conditions will cause a stretching or pulling of pain-sensitive parts and inner structures of the head. These include concussion and other head trauma, strokes, brain tumours and spinal taps (lumbar puncture).

A number of metabolic, toxic or environmental causes are:

The use of certain medications (side-effects)

 Eating or drinking iced foods and fluids

 The use or withdrawal of alcohol ("hangover"), caffeine, or other analgesic drugs (analgesic headaches)

 Breathing in smoke or fumes from chemicals

Repeated exposure to nitrate compounds (found in heart medicine and dynamite; also used in a meat preservative, sodium nitrate – such as in hot-dogs and bacon)

 Exposure to materials containing chemical solvents (for example benzene, turpentine, spray adhesives, rubber cement and certain inks)

Eating foods (such as Chinese food) prepared with monosodium glutamate, a flavour enhancer

 Exposure to poisons such as insecticides, lead and carbon tetrachloride

Use of drugs such as amphetamines

 High altitudes (above 4 500m)

 High blood sugar (hyperglycemia)

 Low blood sugar (hypoglycemia)

 Low calcium levels in the blood (hypocalcaemia)

 Kidney failure (uraemia)

If a headache is caused by a serious illness, other symptoms are often present, such as vomiting, dizziness or changes in vision.

How is it diagnosed?

The headache history is, by far, the most important tool a doctor has to evaluate headache. Keep a headache diary.

In diagnosing headaches, the patient’s history is all important. A careful physical examination will be done to check for clues to possible headache causes and also to check the nervous system. The exam can help determine whether further testing is needed.

People with tension-type, migraine or cluster headaches usually will have a normal physical exam.

Any abnormal results in the physical exam may suggest a possible underlying cause of headache. Abnormal results may include:

 Fever, which may indicate an infection such as sinusitis. Headache with fever, stiff neck, nausea and vomiting may indicate meningitis

 Headache that began suddenly in a person who has not had headaches before, or a dramatic change in an established headache pattern

Headache that follows any form of physical exertion, such as exercise, sexual activity, coughing or bending (these types of headaches are usually not caused by a serious problem, but occasionally they can be related to an aneurysm)

 Abnormal speech, eye movements, walking, co-ordination or reflexes

Abnormal eye exam, which indicates there may be increased pressure inside the skull

 High blood pressure

 Other findings, such as arthritis, which may suggest autoimmune disease

The history and physical exam are all that is needed to diagnose benign headaches, including tension-type and migraine headaches. Additional tests are only needed to help diagnose other conditions which may cause symptoms like those of tension-type and migraine headaches.

Imaging tests, such as MRI or CT scan, may be needed if your doctor suspects there is an underlying organic cause such as an aneurysm or brain tumour (although these are quite rare). Your doctor may order an imaging test if:

  Your headaches continue to get worse despite conventional treatment.

 The part of the physical exam that checks your nervous system is not normal. Most people with tension-type and migraine headaches have normal results in their nervous system exam.

Imaging tests that may be used in these cases include:

Computed tomography (CT)

 Magnetic resonance imaging (MRI)

  Magnetic resonance angiography (MRA)

Any person over the age of 55 with a recent onset headaches should be tested for temporal arteritis by means of a blood test (ESR).

How is it treated?

An initial and fundamentally important step in the management of headache is to differentiate those headaches that are the result of other, often serious, conditions ('secondary' headaches) from headaches that are not caused by an underlying disease process ('primary' headaches).

Although symptomatic treatment of pain is also necessary in secondary headaches, it is crucial to treat the underlying cause. In the case of a brain tumor, this may mean surgical excision or a shunt to reduce raised intracranial pressure; antibiotics for bacterial meningitis; and surgical drainage of an intracranial hemorrhage.

Primary headaches are the far larger group, and include tension headaches and migraine. These headaches are managed symptomatically - there is no underlying disease to also take care of.

Lifestyle

There are several common-sense courses of action that may well prevent headaches in the first place: A change in lifestyle that reduces stress may be enough.

Some patients notice that certain situations or habitual patterns of behaviour are likely to cause headache. Avoiding certain trigger foods and chemical compounds (perfumes, smoke) may be central to the management of migraine. In most people, getting regular exercise, avoiding excessive caffeine and alcohol, stopping smoking and ensuring adequate hydration are cornerstones of treatment, and are just as important as drug management. They also have all sorts of other benefits.

Medication

Drugs for headache are either prophylactic or symptomatic. Prophylactic medications are taken daily and are directed towards preventing the headache from developing in the first place. They are not pain medications. Symptomatic or “abortive” medications are pain medications - analgesics - and are designed to stop the headache once it has started. Often a trial-and-error approach is necessary to match an individual patient with the most suitable medication.

There are a wide variety of prophylactic medications. Tricyclic antidepressants, like amitryptyline, are frequently used, and can ease headache even in those patients not clinically depressed. Other medications include several of the anti-epileptic drugs and the calcium channel blockers. Beta-blockers, used to lower blood pressure in other patients, are effective in migraine.

Once a headache has taken hold, abortive medications are used. These include simple analgesics like paracetamol and aspirin, anti-inflammatories and muscle relaxants. Narcotic analgesics may be necessary for the most severe headaches, but they are best limited to one-off usage, and should not be prescribed longer-term, as they are habit-forming.

Migraine is often associated with intense nausea, and an anti-emetic may be enough to halt a migraine. Medications that act on the caliber of blood vessels have an important place in migraine therapy - the ergot drugs of old have largely been replaced by the newer “triptan” medications like sumatriptan (Imitrex), which has oral, subcutaneous and intranasal forms. Unusual primary headaches like cluster may respond to breathing Oxygen.

It should be mentioned that although there are many efficacious medications for headache, all have side-effects, and so should be used judiciously. In fact, so-called “rebound headache” is a well-recognised result of medication overuse, and if severe, may necessitate hospitalisation for medication withdrawal.

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